One-sixth of the superstar sextet of NBC's Friends, Aniston has become the most successful of the bunch with leading roles in hits like Bruce Almighty, Along Came Polly and The Break Up.
Although better known as a sappy-sweet good girl than daring sexpot, Aniston has tried spicing up herimage more recently.
Following a broken engagement with actor Tate Donovan in the mid-90s, Aniston climbed the rungs of celebrity love with her marriage to Brad Pitt in 2000. The two divorced five years later in 2005, when Pitt left Aniston for his Mr. and Mrs. Smith costar, Angelina Jolie.
Following the breakup, Aniston became involved with her Break-Up costar Vince Vaughn in 2006. The two officially split in October of 2006.
In April 2008, Aniston was spotted around town with John Mayer. In June, it became apparent that things were getting serious when Aniston introduced her new beau to BFF Courteney Cox.
In March of 2008, Aniston and producing partner Kristin Hahn - who have been working together since Aniston was a partner with ex Brad Pitt in the production company Plan B - formed a new production company, Echo Films.
Aniston and her Wanderlust costar, Justin Theroux, took their romance public in the spring of 2011. Theroux proposed on August 10, 2012 -- his 41st birthday.