Matthew McConaughey in The Dallas Buyer's Club
The usually buff Magic Mike star raised eyebrows and concerns when he lost nearly 40 pounds to play Ron Woodruff in 2013's The Dallas Buyer's Club. (Woodruff was a real-life drug addict in the 1980s who contracted HIV and became one of the first-ever AIDS activists.) "I got the means to lose the weight in a really healthy way," he insisted. "I'm eating fresh fish. I'm just eating small amounts. I'm not being starved...I'm taking care of myself."