Bradley Cooper's Love Life

Renee Zellweger

The pair met filming Case 39 in 2006 and began dating three years later. The low-key couple called it quits in March 2011, just as Limitless -- Cooper's first starring role -- hit theaters. "If I had to pick any possible mistress it would be Brad's career," once source told Us. "He worked really hard to get into leading man status."

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