Check out photos of Hollywood's hottest famous pals
John Stamos and Lori Loughlin
They were on-screen lovers on the hit '90s sitcom Full House, and to this day, TV's Rebecca Donaldson and Jesse Katsopolis remain pals. "I consider him one of my best, dearest friends," the actress gushed to Us of Stamos. "Certainly one of my oldest longtime friends."