Their chemistry is so palpable, they have to constantly ward off rumors that they're more than just friends. From Sandra Bullock and George Clooney to Zooey Deschanel and Joseph Gordon-Levitt, meet Hollywood's famous platonic pairs
John Stamos and Lori Loughlin
Full House's Uncle Jessie and Aunt Becky may have dated once when they were 18, but timing has kept their relationship since strictly platonic. Stamos told HuffPost Live in June 2013, "We did have some off timing, but no disrespect to her family and her husband now, I would say that she could be the one that got away." He added, "She's one of my dearest friends, and that's good enough...but I really do adore her. She has a great husband and he's got a lot of money so..."