Credit: Michael Buckner/Getty Images; Kevork Djansezian/Getty Images

Danger, Conan O'Brien: watch your back for Kirstie Alley.

Alley does not take kindly to being the brunt of O'Brien's fat jokes on his Late Night show -- as she told pal Star Jones (and all their online followers) via Twitter during an extended rant.

"ONE BITCH I'm gonna knck [sic] out next time I see her is CONAN O'BITCH O'BRIAN [sic]," Alley rails. "That guy acts like I bit his d*** off."

Jones quips back with a veiled threat of violence against the comedian, "You know Conan probably 'wanted some' and you chumped him...I know a few brothers from Brooklyn who owe me! LOL"

As the Huffington Post points out, O'Brien has joked that Alley's personal motto is "Leave No Ham Behind."

Earlier in the "chat," the former View hostess empathizes with Alley, writing, "Like I don't know what it is like to be called FAT, UGLY & LAZY. Hell...people called me that on TV and in print!"

Onward and upward: Alley is presently filming a reality series for A&E about single motherhood and her struggle to lose weight.

"Kirstie is exactly the kind of star A&E is drawn to," an A&E executive told Variety. "Her personal life has been playing out in the media for years, but this will be the first time she'll be opening up her home to reveal her real life for the cameras."