After stints as a daytime talk show host and as a controversial co-host on The View, Rosie O'Donnell is heading back to a morning show. This time, however, it's on the radio.

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The former stand-up comedian is launching her own daily, two-hour show for Sirius XM Radio this fall. "This is an exciting new adventure -- two hours of talk show entertainment, without having to wear makeup. Perfection," O'Donnell said in a statement to "I can't wait to jumpstart each day with millions of Sirius XM listeners across the country."

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The call-in show, called Rosie Radio, will tackle topics including pop culture, politics and stay-at-home moms.

"Rosie O'Donnell is a powerful, dynamic and entertaining voice and now you can only get her on Sirius XM," the company's president, Scott Greenstein, said. "Rosie's millions of fans will hear her as they never have before and have the chance to call in and talk to her and her intriguing guests. Rosie Radio will entertain, inform, surprise and delight."

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The show, which will air Monday through Friday at 10 a.m. EST, will also include a wide range of guests including celebrities and everyday Americans. O'Donnell's show will join Sirius' lineup of famous hosts such as Oprah Winfrey, Martha Stewart and Barbara Walters, whom she feuded with on The View before her contentious departure in 2007.