LOL! See which hilarious women are taking over Tinseltown
In the early '90s, O'Donnell appeared in films such as A League of Their Own and Sleepless in Seattle. From 1996 to 2002, she hosted an eponymous daytime talk show. An author of three books, O'Donnell also released two Christmas albums. She briefly appeared as a co-host on The View, and from 2011 to 2012, she hosted her own show on the OWN network.
Credit: Warner Bros. Television/courtesy Everett Collection