‘Grey’s Anatomy’: All the Famous Guest Stars You Forgot About

Over the past 15 seasons, many famous faces have visited Grey Sloan Memorial Hospital – some of them even appeared when it was called Seattle Grace Mercy West Hospital!

Shocking TV Exits

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While multiple stars appeared on Grey’s Anatomy for long stretches, others had one-episode stints. During season 6, Demi Lovato – who had already dropped two albums at the time – played a woman incorrectly diagnosed with paranoid schizophrenia. During season 11 (oddly enough), Millie Bobby Brown played Ruby, a girl who saves her mother’s life by calling the hospital when her mom gets hurt, prompting the doctors to walk her through what to do.

Demi Lovato and Millie Bobby Brown on Grey's Anatomy
Demi Lovato and Millie Bobby Brown on Grey’s Anatomy Mitch Haddad/ABC via Getty Images; Frederick M. Brown/Getty Images

Before crushing skulls on The Walking Dead, Jeffrey Dean Morgan crushed hearts as Denny; he first appeared in season 2 and ended up starring in 23 episodes as Izzy’s (Katherine Heigl) love interest. He recurred through season 3 and his last appearance was in season 5. Four seasons later, his wife Hilarie Burton appeared on the show, playing Dr. Lauren Boswell. She even had a quick fling with Arizona (Jessica Capshaw) during her four-episode arc.

TV’s Shadiest Behind-the-Scenes Shakeups

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Watch the video above to find out who else has appeared on the medical drama.

Grey’s Anatomy airs on ABC Thursdays at 8 p.m. ET.

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