The Anchorman 2 actress, 41, and her musician beau, 43, got engaged after two years of dating on Valentine's Day in 2010. They have a 2-year-old daughter together, Sadie Grace, born Jan. 27, 2011.
The Emmy-nominated star -- who recently quit NBC's Up All Night -- has credited her new husband, a founding member of '90s rock band Porno for Pyros, with helping to get her through her battle with breast cancer. (Applegate was diagnosed with the disease in 2008 and underwent a double mastectomy that same year.)
"I have a small but mighty support system and Martyn has really been an incredible part of my life," Applegate told Us Weekly in 2010. "Without him, I don't know if I could've gone through any of it. He came around at a time when there was a lot of loss in my life on many levels, so he's been a really incredible help."
This is the second marriage for both. Applegate was previously married to Johnathon Schaech for six years.