Diem Brown on February 21, 2012 in Hollywood, California. Credit: Gregg DeGuire/FilmMagic

Such sad news.

MTV star Diem Brown is battling ovarian cancer again.

"My doctor just called me and I have Cancer again. Didn't think ovarian cancer could come back. Please get internal ultrasounds every year," she tweeted Tuesday.

The Challenge star, now 29, was first diagnosed with ovarian cancer at the age of 22.

"I know I will be fine I beat Cancer once and I'm going do it again!" she wrote. "I know God has a reason for every speed bump in life and I'm ready. MedGift."

Brown is the founder of MedGift charity organization, which is a gift registry for sick patients.

"Any patient, from cancer to car accidents to wounded warriors, can list their hospital bills, ask for wigs, wheelchairs, certain foods or cosmetics. Their friends, family and co-workers can then go on and select an item from their patient gift registry, without even having to ask," she told Fox News about the charity in February. "I wanted to make MedGift mainstream, so the second someone has a medical misfortune, they know where to turn."

On May 14, Brown tweeted, "Don't care if it's TMI but ladies get a internal ultrasound. I've put one off and it sucks to find out I need surgery to remove a large cyst. Praying for the best."