Chelsea Handler has potty problems!

When her pal Heather McDonald, 40, needs a place to crash after an argument with her husband, Handler offers up her home on Sunday's episode of After Lately.

On the ladies' agenda? Sipping on margaritas and watching a Lifetime movie in Handler's bed.

"This is really fun. It's like sleepover sisters!" an excited McDonald says while noshing on popcorn. "It's really warm under this comforter."

"I just peed," Handler, 36, says nonchalantly. "I'm sorry. I was laughing and a little bit came out. It'll dry!"

After Lately airs Sunday night at 11 p.m. (EST) on E!