The bitch is back on Melrose Place.

In a clip from Heather Locklear's much-anticipated return to the CW series that made her famous, the 47-year-old actress reprises her role as scheming ad vixen Amanda Woodward -- and goes toe-to-toe with the new hot girl in town, Ella, played by Katie Cassidy.

"Miss Woodward, it is an honor to finally meet you," Cassidy's PR exec bumbles. "Your article in Vanity Fair is pretty much what inspired me to become a publicist." (Watch above.)

Read Us' review of Locklear's performance.

"Shockingly, I didn't call you here for your life story," Locklear snipes back in the episode, to air Nov. 17. "Although your absentee father and pill-popping mother make for a very juicy tale."

Woodward returns to Melrose to stay in the penthouse while construction on her home is being completed. Locklear's character appeared to have been killed off the show in May 1999 but was later spotted with Peter (played by current real-life beau Jack Wagner) on a sunny, secluded island.

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"The truth is, I really miss this place," she tells the tenants, who include soon-to-leave Ashlee Simpson-Wentz. "And I can't wait to become a part of each and every one of your lives."

During filming, an insider told Us Weekly the role is a "a great comeback" for the actress, who faced a DUI charge that was later dismissed and sought treatment for anxiety last year.

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Said the source: "She is in great spirits and good shape. This is a perfect time to show everyone how well she is doing."

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