Curtis '50 Cent' Jackson attends the annual Charity Day at Cantor Fitzgerald on Sept. 11, 2015, in New York City. Credit: Noam Galai/Getty Images

Yikes! Meek Mill is never shy when it comes to picking fights — but he picked the wrong target, once again. In his new song “Gave ‘Em Hope,” the Philly rapper throws some not-so-subliminal jabs at 50 Cent, including a line that refers to Vivica A. Fox’s comments that 50 might be gay.

50 Cent took to Instagram on Sunday, January 17, to respond to Mill's diss track. The “Candy Shop” rapper, 40, posted an image of Mill's face Photoshopped over the poop emoji with the caption, “LMAO Hey s--t head, your career is over already. You better focus on getting Nicki [Minaj] pregnant so you can at least get child support girl.”

50 Cent has since posted a total of nine memes poking fun at Mill, 28, including one where the rapper is getting slapped and another of him crying.

Mill, Minaj's boyfriend, quickly replied with an Instagram photo of himself holding stacks of cash, captioned, “U pop s--t on social media 24/7… U never in the places everybody b at… The whole queens say you a rat…”

Mill added, “U going broke and you miserable… U really miserable bro… [Floyd] Mayweather ain’t got tickets for you no more… Ya liquor is piss… U really miserable and don’t really have friends.”

U pop shit on social media 24/7 ... U never in the places everybody b at.... The whole queens say you a rat.... Ross baby mom hit you for that check you sick .... Ross finished you "career over? How dare you speak on that? .... All you artist that came under you broke" ya son hate you smfh! Ya swag on below "0" lol hold up..... U always hating on puff and Hov other go getters from ya city...... U going broke and you miserable .... U really miserable bro.... You like 40 on the internet all day Mayweather ain't got tickets for you nomore .... Ya liquor is piss... U really miserable and don't really have friends ... You scared to play the mixes everybody b at! U never played with me in person because u know how we rocking lol I'm done wit you ... This my last insta-fingers post for a min lol Norm Kelly hold up...... Young black dude that came from nothing vs old white racist man from Toronto.... I got more money than you already? You took the real "L" in life champ! Oh fif all y'all dudes do is talk about Nicki ... This just my real life my fault for snapping on y'all weirdos! Hov gave you a half of bar bro ski... I bet any amount of money queens would trade me for you! "You the one made it cool to b a hater" I'm out Sincerely -instafingers @iamdiddy @ceoslow stop letting this dork play around ... He already been shot 9 times lol he like a vegetable or something .... @irvgotti187 can you clarify that he told on y'all? We need answers!

A photo posted by Meek Mill (@meekmill) on

Mill is no stranger to social media beefs with fellow hip-hop artists. In July, he publicly accused Drake of using ghostwriters to write his verse on their song “R.I.C.O.” Drake, 29, released two diss songs in response — “Charged Up” and “Back to Back,” the latter of which is nominated for Best Rap Performance at the 58th annual Grammy Awards.

A video posted by 50 Cent (@50cent) on

A photo posted by 50 Cent (@50cent) on

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