Not to mention, the actress' quote to Guiliana Rancic about her underwear at Sunday's SAG Awards ("It is just that they are very tiny, and you could say there is almost no underwear, but they are underwear!") just adds fuel to the red-hot fire.
Shockingly, it took AskMen.com readers a year to come around -- the 39-year-old star held down the #3 spot on the 2010 list, right below Mila Kunis and Blake Lively.
But this year, the Colombian beauty beats out Sports Illustrated model Kate Upton, The Girl with the Dragon Tattoo's Rooney Mara and Victoria's Secret model Miranda Kerr, who held the number 2, 3, and 4 spots, respectively.
A crush-worthy Scarlett Johansson nabbed the #7 spot with Kim Kardashian at her heels at #8. Megan Fox was down near the bottom of the list at #96, two spots above Pippa Middleton, who was a landslide away from her older sister Kate Middleton, who came in at #11.
Surprisingly absent from the poll? Fan-favorites Jennifer Aniston and Angelina Jolie.
Find out which other stars made the list at AskMen.com and tell Us: Do you think Vergara has what it takes to be 2012's most desirable female celeb?