Talk about getting hands-on experience!

In Horrible Bosses, Jennifer Aniston plays a sex-crazed dentist who flaunts a major lack of boundaries with her put-upon male hygienist (Charlie Day). The actress, 42, violates one sexual harassment code after another in a brand-new trailer for the raunchy, dark comedy (in which Aniston shot a topless scene, an insider told Us Weekly).

In the clip, Aniston "accidentally" squirts water at Day's crotch, suggestively eats a banana in lingerie, and even forces a male patient to grope her breasts.

Day commiserates with other pals (Jason Bateman and Jason Sudeikis) with "horrible bosses" (Kevin Spacey and Colin Farrell) as they plot a radical solution to their job woes: murder!

Watch the raunchy clip now.