Kermit the Frog and Miss Piggy's long-awaited return to the silver screen was no match for the Twilight juggernaut.
The Muppets -- costarring Jason Segel and Amy Adams -- debuted in second place with $43.5 million, falling behind The Twilight Saga: Breaking Dawn - Part 1, which earned $61.3 million over the five-day holiday.
The vampire love story -- starring Kristen Stewart, Robert Pattinson and Taylor Lautner -- has earned $220.3 million since its November 18 debut.
Family friendly films dominated the box office this weekend, with Happy Feet Two falling one spot to third place with $18 million. The 3-D movie Arthur Christmas earned $16.5 million in its opening weekend, while Martin Scorsese's Hugo -- starring Chloe Moretz and Jude Law -- debuted in a disappointing fifth place with $15 million.
Rounding out this week's Top 10: Jack & Jill (No. 6, $14 million), Immortals (No. 7, $13.3 million), Puss in Boots (No. 8, $11.5 million), Tower Heist (No. 9, $10 million) and The Descendants (No. 10, $9 million).
Tell Us: Which movie did you see this weekend?