The actors, who costarred in 2011 dramedy The Oranges alongside Catherine Keener and Hugh Laurie, have been "hanging out," the source tells Us.
"They were always close and friendly," the insider added, noting that the pair would hang out on occasion during shooting for the film.
Brody, 33, first landed in the spotlight as lovable comic book geek Seth Cohen on the WB's hit The O.C. back in the early 2000s. He was most recently linked to director Lorene Scafaria, who wrote Nick and Nora's Infinite Playlist, back in 2010.
Gossip Girl actress Meester, meanwhile, previously dated actor Aaron Himelstein, though the 26-year-old parted ways with him over the holidays.
And even though she and Brody have been keeping their relationship out of the public eye, the new couple has already been making their rounds, traveling together to Bangkok earlier this year and taking in art exhibits at the Los Angeles County Museum of Art on Friday, Feb. 1.
Pick up the new issue of Us Weekly, out on stands Friday, to read more about the couple's newfound love.
For access to all our exclusive celebrity videos and interviews – Subscribe on YouTube!