Credit: Michael Loccisano/; Duffy-Marie Arnoult/

Chelsea Handler isn't ready to come clean about 50 Cent.

On Tuesday, a reliable source told that the E! talk show host, 35, has "a hookup thing" with the rapper, 35 (they were spotted getting cozy Sunday at a New Orleans bar).

The next day, when photographers asked him about Handler, he simply smiled but didn't deny a romance.

Handler is playing coy as well.

"Everyone, calm down," she Tweeted Wednesday night. "I met with Mr. Cent about a potential project. There's nothing to report yet. I'll let you know if there is."

But just last month, the comedian spoke candidly about the "incredibly cute" rapper during a roundtable discussion on Chelsea Lately.

"Listen, everybody knows I'm trying to go black hard, okay? I'm not trying to pretend that I don't want to do that," she joked. "Me and 50, we're working something out. Things are going to go down."

She then claimed the hip-hop star sent her 15 vases of flowers with the phrase "I love you, 50 Cent" inscribed on each card.

"I had to give them away. There were too many," she explained. "But obviously now I'm going to have to f--k him."