Us Poll: Who Should Replace Charlie Sheen on Two and a Half Men?

See Results »
John Stamos
55% 8362
Rob Lowe
36% 5463
Jason Alexander
10% 1454
Entertainment March 8, 2011 AT 7:22PM
Who Should Replace Charlie Sheen on Two and a Half Men? Credit: Jason LaVeris/FilmMagic; Jemal Countess/Getty; Michael Loccisano/Gett

One day after CBS dropped Charlie Sheen from their lineup and declared his services on Two and a Half Men no longer necessary, a handful of A-list replacement names have already been floated.

Though John Stamos was rumored to be in the running to replace Sheen, 45, as of last week, TMZ.com reports Two and a Half Men's creator, Chuck Lorre, has been in talks with Parks and Recreation's Rob Lowe to assume the role of Charlie Harper.

For his part, Stamos dispelled contract talks via Twitter, blogging that "Contrary to the rumors, i am not replacing charlie sheen on two and half men. however, martin sheen has asked me to be his son."

PHOTOS: Charlie Sheen's biggest controversies

But Stamos is not the only actor taking to the micro-blogging site to offer their thoughts. Seinfeld's Jason Alexander jokingly threw his hat into the ring on Monday.

"As an act of pure selflessness, I would like to volunteer my services to step into his role, so that millions of fans around the world will not be disappointed," Alexander blogged. "Finding myself in this generous state, I will forego contract negotiations and merely assume the unfinished contract of Mr. Sheen, himself…I could also play the "half-man" of the title, as I am considered diminutive by most measures."

VIDEO: The actor's wacky TV interview antics

While no casting decisions have been made and the future of CBS' highest-rated sitcom remains to be seen, Sheen has publicly vowed to seek vengeance on Warner Bros. and CBS after Two and a Half Men was put on hiatus February 24 as a result of Sheen's erratic "statements, conduct and condition."

By Allison Corneau for UsMagazine.com. For more Channel Surfing, click here.

Tell Us What You Think

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  • April 29, 2011 - 1:21pm Pauline Burch Brown

    What about Paul Reiser? He's pretty fun. I don't really think the other choices would make it...

  • March 20, 2011 - 12:41pm Donna Bell Martin

    MATT LEBLAC (Joey from Friends) should replace Charlie Sheen....Has CBS even thought of him? He would be GREAT.

  • March 13, 2011 - 6:40am Paul Braden

    I think the plot should be that Charlie has moved away to live with Rose and live off of her money. Charlie calls Jake and gives his house, royalties, car, and bank account to him. Jake becomes the new Charlie and continues to twist Alan's nuts, allowing Alan to live in the house with conditions.

  • March 11, 2011 - 9:32pm Angela Michael

    no one can replace charlie sheen i wouldn't even watch the show if was replace he makes the show hes the best

  • March 10, 2011 - 10:15am Louis Martin

    After Sheen's Departure the Show isn't going to be The Same, period.

  • March 09, 2011 - 1:08pm Sylvia Wadas

    I agree with Nirmala -- Robert Downey Jr would make a good replacement as well!

  • March 09, 2011 - 1:06pm Sylvia Wadas

    Brad Garrett!!

  • March 09, 2011 - 11:33am Sharie Barnett

    NO ONE- CANCEL THE SHOW

  • March 09, 2011 - 11:31am Denise Bianco

    My vote goes to Mark Paul Gosselaar!!!!

  • March 09, 2011 - 9:38am Jincy Cook-Manchester

    I think no one should replace Charlie Sheen ~ I think a new character should be created to take his place !

  • March 09, 2011 - 9:36am Cinnamon Everett

    Just cancel the show..Charlie IS the show. The others are great support to the show no doubt but no one could replace Charlie..they would have to come up w/an all new character all together which I still don't think most would like..just cancel it.

  • March 09, 2011 - 9:35am Cristina Hernandez

    No one. This show is garbage.

  • March 09, 2011 - 9:32am Sabrina James

    Although Charles messed up big time you need someone more funnier than the three that are in the running. That show need to keep up the pace it's in now. If you put one of them in it you might loose the audiance that watch now

  • March 09, 2011 - 9:27am Nicole Clarke

    The comedian on Chelsea Handler said it best...CHRISTIAN SLATER is the best person to play Charlie's part.

  • March 09, 2011 - 9:22am Tammy Babb

    James (JIM) Belushi

  • March 09, 2011 - 9:20am Tammy Babb

    Jim Belushi!! He would be perfect!

  • March 09, 2011 - 8:45am Kay Marie Speed

    Sean Penn would be great for that role. Good idea guys!!!!! I also like Scott Disick in the role. He's mostly known for being Kourtney K's boyfriend, but he is rather funny, and he's a pretty boy.

  • March 09, 2011 - 8:27am Victoria Owens

    Please just cancel this terrible show. It caters only to the lowest common denominator of humanity. Considering the show is "CBS's highest rated sitcom", I am scared for America. Is this really what amounts to entertainment? Although I do suppose it is better than The Bachelor or Survivor. What has this world come to?

  • March 09, 2011 - 8:21am Sherri Pharis Treece

    However, I DO kinda like Thereses' idea with Sean Penn.

  • March 09, 2011 - 8:18am Sherri Pharis Treece

    No one can replace Charlie and have the show EVEN compare. JMO

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