Johnny Galecki and Kelli Garner have called it quits Credit: Gregg DeGuire/WireImage

Big Bang Theory Johnny Galecki and Pan Am actress Kelli Garner have decided to split after more than two years together, a source confirms to Us Weekly.

Although the couple, who first stepped out publicly in March 2012 after months of quietly dating, have called it quits, a source tells Us "Johnny and Kelli are still best friends" and adds that the split was amicable.

The breakup comes just months after the duo were spotted packing on the PDA during a Mexico getaway in January, days after attending Galecki's ex and The Big Bang Theory costar Kaley Cuoco's wedding to Ryan Sweeting.

Galecki attended the 2014 Emmy Awards and multiple parties with friends on Aug. 25.