10 Must-Watch Comedy Movies on Prime Video (April 2026): ‘Mr. Mom’ and More

Being John Malkovich is such a bizarre film that it’s astonishing it was ever made. This was the first movie made by director Spike Jonze and screenwriter Charlie Kaufman, the pair who somehow convinced John Malkovich to play himself in a story about people who enter his mind to experience his life. Craig Schwartz (John Cusack) is the first man to discover the portal to Malkovich’s subconscious, but he stupidly shares it with his coworker, Maxine Lund (Catherine Keener), because he’s desperately in love with her.

The problem for Craig is that he’s already married to Lotte Schwartz (Cameron Diaz), and she’s falling in love with Maxine while inhabiting Malkovich’s body. As for Malkovich, he has no idea what’s happening to him or who he should trust. But he’s about to get a first-hand look at his own mind.

Being John Malkovich is streaming on Prime Video.

You may not be able to get past how young Michael Keaton looks in Mr. Mom, which was one of his first breakout films. In this early ’80s comedy, the domestic roles are reversed when Jack Butler (Keaton) is laid off from his job at the auto plant while his wife, Caroline Butler (Teri Garr), reenters the workforce with a higher-paying job at an ad company.

That leaves Jack to stumble his way through life as a house husband and caretaker for his kids, while Caroline has to contend with an overly amorous boss, Ron Richardson (Martin Mull). That places considerable strain on Jack and Caroline’s relationship, but Keaton and Garr make the entire film worthwhile.

Mr. Mom is streaming on Prime Video.

If the name Jeffrey Manchester means nothing to you, it’s probably because his modern-day gentleman thief routine played out over 25 years ago. Roofman is a crime comedy that casts Channing Tatum as Manchester, an army veteran who perfected a way of breaking into McDonald’s restaurants and robbing the staff at dawn — but politely.

While living in a Toys “R” Us to avoid the police, Manchester meets and falls for Leigh Wainscott (Kirsten Dunst), a single mother and a store employee. In Wainscott and her children, Manchester sees a chance to have the family life that he left behind. But he has a knack for making bad decisions, and he can only hide from the consequences for so long.

Roofman is streaming on Prime Video.

It’s probably best not to think about how 73-year-old Liam Neeson could play the son of Leslie Nielsen and Priscilla Presley‘s characters when they didn’t meet until 1988. So you’ll just have to go with The Naked Gun when it portrays Neeson as Frank Drebin Jr. in a sequel rather than a full remake of the original film.

Like his father, Drebin is the rare combination of idiocy and competency that usually allows him to get the job done. In the aftermath of a software engineer’s suspicious death, Frank gets close to the man’s sister, Beth Davenport (Pamela Anderson). From there, Frank literally stumbles into a conspiracy surrounding the dead man that has wider implications if he can’t stop it.

The Naked Gun is streaming on Prime Video.

Most of the humor in Novocaine comes from the insane things that Nathan Caine (Jack Quaid) puts his body through in the name of love. Nathan may not be able to feel pain, but the things he experiences are enough for the audience to feel it vicariously.

Nathan just can’t help himself, because the woman he loves, Sherry Margrave (Amber Midthunder), has been kidnapped by a bank robber. Although Nathan only has a vague idea of how to fight, he won’t let that stop him from trying to track down the man who took Sherry. Nathan’s unique “gift” might be the only thing that gets him out of this alive.

Novocaine is streaming on Prime Video.

The Pickup boasts a comedy dream team of Eddie Murphy and Pete Davidson as Russell Pierce and Travis Stolly, a pair of mismatched armored car drivers. On their first day out together, the veteran and the rookie are attacked by a criminal mastermind named Zoe (Keke Palmer), as well as her associates, Banner (Jack Kesy) and Miguel (Ismael Cruz Córdova).

Zoe has been planning this robbery for a long time, and she has an even deeper agenda than either Banner or Miguel realizes. That may force Russell and Travis to reevaluate how far they’re willing to go to protect their truck, and whether they can believe Zoe when she explains her endgame.

The Pickup is streaming on Prime Video.

Director Rian Johnson assembled an all-star cast for his comedy mystery, Knives Out, with James Bond actor Daniel Craig in the lead as a famous detective named Benoit Blanc. Someone has anonymously hired Benoit to investigate the murder of a wealthy author, Harlan Thrombey (Christopher Plummer).

Harlan’s beloved nurse, Marta Cabrera (Ana de Armas), knows all about the murder because she’s been framed for the crime. Things look even more suspicious when Marta is named in Harlan’s will as the sole recipient of his fortune. Someone in the family must have been responsible for Marta’s plight, and she needs to figure out who before Benoit’s investigation can lead back to her.

Knives Out is streaming on Prime Video.

The Little Hours may be set in the 14th century, but it’s more concerned with laughs than historical accuracy. It’s very loosely based upon The Decameron and features Aubrey Plaza, Alison Brie and Kate Micucci as a trio of nuns whose carnal desires can’t be contained by the church.

To escape his brutal master, a young man named Massetto (Dave Franco) begins working for the convent while pretending to be deaf and mute. His presence gives the nuns someone to lust over when they aren’t giving in to temptation with each other.

The Little Hours is streaming on Prime Video.

Five decades ago, the Monty Python comedy group unleashed one of the all-time great comedy movies: Monty Python and the Holy Grail. Graham Chapman, John Cleese, Terry Gilliam, Eric Idle, Terry Jones and Michael Palin all play multiple roles in this hilarious take on Arthurian lore.

Not even King Arthur (Chapman) is immune to ridicule in this retelling. Arthur and his men are on a quest to find the Holy Grail, and they do some very silly things along the way. Arthur’s duel with the Black Knight (Cleese) is particularly quotable even after 50 years. This is a comedic masterpiece that few films have ever matched.

Monty Python and the Holy Grail is streaming on Prime Video.

Monty Python strikes again with Life of Brian, a spoof of Biblical proportions that centers on Brian Cohen (Graham Chapman), a man who had the misfortune of being born on the same day as Jesus (Kenneth Colley). At birth, Brian is mistaken for the messiah, and it’s a recurring theme throughout his life.

Brian’s infatuation with Judith Iscariot (Sue Jones-Davies) leads him into the revolutionary factions who want to break Judaea free from Roman rule. From there, Brian’s story becomes increasingly absurd, including his face-to-face meeting with Rome’s governor of Judaea, Pontius Pilate (Michael Palin). This movie is hysterically funny for reasons you’ll just have to see for yourself.

Life of Brian is streaming on Prime Video.