Jennifer Aniston's Horrible Bosses Is a Box Office Hit!

Jennifer Aniston is lucky in love lately (with new guy Justin Theroux) -- and her box office clout is on an upswing, too!

The 42-year-old star's latest flick, Horrible Bosses, nabbed $28.1 million in its opening weekend, according to early estimates, making it the third biggest comedy of the year so far.

But the film didn't, however, land in first place. That honor went to Transformers: Dark of the Moon, which earned an additional $47 million its second weekend out. Kevin James' talking-animal comedy Zookeeper, which cost a surprising $80 million to produce, landed in third place with a $21 million box office haul.

Aniston earned favorable reviews for her turn as one of three bad, bad employers in Horrible Bosses, costarring Jason Sudeikis, Colin Farrell, Jason Bateman and Kevin Spacey.

The actress played against type as Dr. Julia Harris, a dentist who sexually harasses her male employee, played by Charlie Day.

Tell Us: Did you see Horrible Bosses this weekend?