The CBS smash hit comedy premiered on Sept. 19, 2005 and ran for nine seasons until March 31, 2014. The series has won seven Emmy Awards, five People's Choice Awards, and racked up several other nominations. See stars Josh Radnor, Jason Segel, Cobie Smulders, Neil Patrick Harris, Alyson Hannigan and others then and now
Alyson Hannigan: Now
The redhead star reprised her American Pie role in the franchise's next three installments -- American Pie 2, American Wedding, and American Reunion. Although HIMYM was her main priority, she did lend her voice to animated series' The Simpsons, American Dad!, and Robot Chicken.
Credit: Cliff Lipson/CBS