Jenny Mollen is still traumatized by her GLP-1 experience after she was hospitalized with blood clots.
“I was microdosing the GLPs. I was also taking other peptides,” Mollen, 47, recalled of the June 2025 incident during an appearance on the Wednesday, June 24, episode of the “Let’s Talk Off Camera With Kelly Ripa” podcast. “But I think that something happens with your period. Maybe it’s just the perimenopausal situation.”
Mollen remembered, “Suddenly I was, like, hemorrhaging. It was, like, blood clots the size of dinosaur eggs. It was so scary.”
The actress, who was married to Jason Biggs at the time, said she “felt like I was laying an egg” when she went to the bathroom. (Us Weekly confirmed in May that Mollen and Biggs called it quits after 18 years of marriage.)
“You felt it coming out of you,” Mollen said on the podcast. “So I run to the bathroom and I am literally sitting on the toilet and I hear this plop and just blood everywhere.”
Mollen said she was “screaming” for Biggs, 48, to come help her. When he arrived, he couldn’t help but match her energy — the author said her then-husband was “screaming like it’s a horror movie.”
Despite being nervous about what was happening, Mollen revealed she continued to go about her day “having these blood clots” at home.
At night, however, her health deteriorated. “I’m like, baby, ‘I think I’m losing too much blood,’” she recalled telling Biggs.
Mollen explained that Biggs was lying in bed and “passed out next to me” and woke up to say, “You’re fine,” noting he had no idea what was happening.
“Meanwhile I walk to the bathroom to try to pee. I have a vasovagal reaction. I passed out on the floor,” Mollen continued. “I’m calling him. I’m like, ‘Jason, Oh, my God, I’m unconscious.’”
Biggs jumped into action, reminding Mollen that their two sons, Sid, 12, and Lazlo, 8, were asleep so he wanted to avoid calling an ambulance and waking them up if possible.
“I’m laid on the bathroom floor. Jason’s like, ‘Jenny you have to get up. You have to let me take you to the car. I’m going to take you to the emergency room,’” Mollen recalled, telling host Kelly Ripa that she “absolutely” could not walk.
Mollen said she fainted again, which is when the American Pie actor called the ambulance and she was transported to the hospital on a gurney.
Mollen and Biggs were able to make it home around 6 a.m. the next morning before their son was sent off to camp, but the experience has remained with her.
“That night was harrowing,” Mollen said on Wednesday.
She noted that the reason she was on a GLP-1 to begin with — along with “a cocktail of peptides” — was because she has hyper thyroid and is autoimmune.
Mollen was on Tirzepatide, a GLP-1 that can regulate a person’s blood sugar, appetite and digestion, and is typically used to treat type 2 diabetes and obesity. In recent years, many started to use GLP-1s for weight loss.
“I don’t know if it was the GLP-1 necessarily. I think it was because I think it was messing with my hormones a little bit,” Mollen concluded. “I think had I stayed on it I would have been fine. But getting off it and then back on it is what screwed me.”
Mollen previously opened up about her health scare in June 2025, after returning home from the emergency room.
“I just posted a follow-up to my piece about Tirzepatide and microdosing,” Mollen wrote via her Instagram Story at the time. “I had a lot of unanswered questions about it [that] just ironically got answered for me in the form of a trip to the ER two nights ago … I’m in such a f***ing haze. It’s been a crazy 48 hours.”
She revealed she was hospitalized after losing one-fourth of her blood after going off the GLP-1 in preparation for a colonoscopy.
Prior to her emergency room stay, Mollen expressed concerns about how the GLP-1 was affecting her mental state.
“When I started Tirzepatide, the first thing I noticed was that I was crying more frequently. I couldn’t control the tears that would pour out of me when talking about subjects ranging from kids to open-faced tuna melts,” she wrote via a June 2025 Substack. “I also noticed this underlying anxiety that would, without warning, after no more than one cup of espresso, take over my body and have me pacing in the kitchen like I’d just snorted an eightball of cocaine.”
