Stars Who've Had Mastectomies

Christina Applegate

Upon being diagnosed with breast cancer in April 2008 at age 36, the Married With Children alum at first opted to have a lumpectomy. She later learned, however, that she was a carrier of the BRCA1 gene mutation. Armed with that information, she chose to have both breasts removed in a bilateral mastectomy, followed by reconstructive surgery a few months later. "It can be very painful," she told Oprah Winfrey in 2008. "It's also a part of you that's gone, so you go through a grieving process."

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