Richmond confirmed the news via Facebook Sunday morning, writing, "He was surrounded by all of his brothers and sisters, one of his nieces and several other loved ones. We were playing music for him and he passed during David Bowie's Starman. As per his wishes, we cheered at the moment that he transitioned to another dimension."
Us Weekly rounds up Alexis' five most memorable roles below.
1. The Wedding Singer, 1998
The Los Angeles native's most famous role was in The Wedding Singer, where she played a Boy George impersonator alongside stars Adam Sandler and Drew Barrymore. Alexis later reprised her role in the comedy duo's 2014 film Blended.
After news broke of Alexis' death, Boy George posted a tribute on Twitter, writing, "R.I.P my sister Alexis Arquette. Another bright light gone out far too soon. Love to the family and all that loved Alexis."
2. Pulp Fiction, 1994
Alexis had a brief (but memorable) role as an unidentified man in Pulp Fiction. She played a young drug dealer who popped out of a bathroom in a failed attempt to shoot Vincent (John Travolta) and Jules (Samuel L. Jackson). Alexis' sister Rosanna also starred in the movie as Jody.
3. Bride of Chucky, 1998
The LGBT activist played the dual roles of Howard Fitzwater and Damien Baylock in Bride of Chucky, the fourth film in the Child's Play horror franchise. Damien was one of Tiffany's (voiced by Jennifer Tilly) love interests before Chucky (Brad Dourif) killed him and dumped the body in a river.
4. Down and Out in Beverly Hills, 1986
Alexis made her big-screen debut in an uncredited role as Alexis, Max's (Evan Richards) androgynous pal and bandmate, in Down and Out in Beverly Hills. The comedy — which starred Nick Nolte, Bette Midler and Richard Dreyfuss — was the first ever R-rated film released by Walt Disney Studios.
5. Last Exit to Brooklyn, 1989
At age 26, Alexis landed a major role in Last Exit to Brooklyn, a 1950s-inspired movie about prostitutes, union workers and drag queens. She played Georgette in the controversial drama, which was based on Hubert Selby Jr.'s 1964 novel of the same name.
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