Kailyn Lowry made her first television appearance in 2010 during season 2 of 16 & Pregnant. She and then-boyfriend Jo Rivera were expecting their first child. In January 2010, they welcomed Isaac Elliot Rivera. Soon after, she split from Jo, and Kailyn then landed a role on Teen Mom 2. During the follow-up series, she married Javi Marroquin in 2012, while she was pregnant with their first child. In November 2013, they welcomed son Lincoln Marshall.
After suffering a miscarriage with their second child, the pair went through many ups and downs and divorced in 2016. In 2017, she entered a relationship with Chris Lopez and they welcomed their first son together, Lux Russell, in August 2017.
In February 2020, she announced that she and Chris are expecting another child, a boy, but they are not together.