Video: Chelsea Handler: Reese Witherspoon "Is Driving Me Crazy!"

Entertainment January 20, 2012 AT 1:44PM

Reese Witherspoon is one of Chelsea Handler's closest celebrity pals, but in a clip from Sunday's all new episode of After Lately, the 35-year-old Oscar winner becomes her biggest nightmare.

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The problem: Witherspoon enlists the help of Handler's writing staff to prepare a speech, but her perky demeanor grates on Handler, 36. "She is driving me crazy!" Handler complains behind Witherspoon's back. "She is so awful."

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The comedienne and bestselling author ignores her employees' polite suggestion to confront Witherspoon, explaining: "What am I supposed to do? I'm gonna go tell Reese Witherspoon that I think she sucks? She's a mess!"

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Will Witherspoon catch Handler badmouthing her? Watch the clip (above) to find out and tune in for an all-new episode of After Lately Sunday at 11 p.m. EST on E!.

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  • January 21, 2012 - 7:48am Mai Lara Mock Clark

    I hope Reese does find out about Chelsea talking behind her back. She doesn't need friends like that and for that matter no one does. They aren't your friends if they talk badly about you behind your back. Some friend.

  • January 20, 2012 - 8:47pm Jennifer R Willis

    i would pick reeses for a bff shes smart caring and if she made me something hiomeade i would be thrilled cant stand chelsea your boring

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